METASTASIS PARU PADA KARSINOMA PAYUDARA: PERAN PENCITRAAN DALAM MENANGANI KASUS KETERLAMBATAN DIAGNOSIS
DOI:
https://doi.org/10.33096/gmj.v7i2.206Kata Kunci:
Breast Carcinoma, lung metastasis, radiological findingsAbstrak
Background: Breast cancer is still the second leading cause of death, with most deaths caused by breast cancer being due to complications associated with metastasis. The target organ of metastasis that often occurs in breast cancer is the lung. Imaging modalities are essential to see breast cancer with lung metastasis and determine early intervention.
Objective: Report on the case of a 60-year-old female patient with lung metastasis of breast carcinoma at Bethesda Hospital, Yogyakarta.
Case Description: A 60-year-old female patient presented with complaints of shortness of breath on exertion and weight loss. The radiological finding was consistent with a lung metastatic lesion.
Conclusion: Early diagnosis of breast tumors and lung metastases is crucial for effective treatment and a positive prognosis due to a much lower chance of death as well as higher survival rates in patients with smaller tumors at the time of diagnosis. Imaging using ultrasound-assisted mammography can be the primary modality for the diagnosis and screening of breast cancer, while for the detection of lung metastases, plain chest X-ray can be used as the primary modality for diagnosis and CT can be a supporting imaging method for the presence of smaller metastatic nodules.
Referensi
DeSantis CE, Ma J, Gaudet MM, Newman LA, Miller KD, Goding Sauer A, et al. Breast cancer statistics, 2019. CA: A Cancer Journal for Clinicians. 2019;69(6):438–51.
Peinado H, Zhang H, Matei IR, Costa-Silva B, Hoshino A, Rodrigues G, et al. Pre-metastatic niches: organ-specific homes for metastases. Nature Reviews Cancer. 2017 May 1;17(5):302–17.
Practice Bulletin Number 179: Breast Cancer Risk Assessment and Screening in Average-Risk Women. Obstet Gynecol. 2017 July;130(1):e1–16.
Menta A, Fouad TM, Lucci A, Le-Petross H, Stauder MC, Woodward WA, et al. Inflammatory Breast Cancer: What to Know About This Unique, Aggressive Breast Cancer. Surg Clin North Am. 2018 Aug;98(4):787–800.
Jin L, Han B, Siegel E, Cui Y, Giuliano A, Cui X. Breast cancer lung metastasis: Molecular biology and therapeutic implications. Cancer Biol Ther. 2018 Apr 30;19(10):858–68.
Gerull WD, Puri V, Kozower BD. The epidemiology and biology of pulmonary metastases. Journal of Thoracic Disease [Internet]. 2021 Apr [cited 2025 July 10];13(4). Available from: https://jtd.amegroups.org/article/view/39409
Iranmakani S, Mortezazadeh T, Sajadian F, Ghaziani MF, Ghafari A, Khezerloo D, et al. A review of various modalities in breast imaging: technical aspects and clinical outcomes. Egyptian Journal of Radiology and Nuclear Medicine. 2020 Apr 16;51(1):57.
Haryati H, Satrio Baringgo D. Solitary Pulmonary Nodule: Is It Benign or Malignant? Respir Scie. 2023 Nov 4;4(1):65–79.
Mann RM, Kuhl CK, Moy L. Contrast‐enhanced MRI for breast cancer screening. Magnetic Resonance Imaging. 2019 Aug;50(2):377–90.
Sharara RS, Hattab Y, Patel K, DiSilvio B, Singh AC, Malik K. Introduction to the Anatomy and Physiology of Pulmonary Circulation. Crit Care Nurs Q. 2017;40(3):181–90.
Chen H, Huang S, Zeng Q, Zhang M, Ni Z, Li X, et al. A retrospective study analyzing missed diagnosis of lung metastases at their early stages on computed tomography. Journal of Thoracic Disease [Internet]. 2019 Aug [cited 2025 July 10];11(8). Available from: https://jtd.amegroups.org/article/view/31030
Bleicher RJ. Timing and Delays in Breast Cancer Evaluation and Treatment. Ann Surg Oncol. 2018 Oct;25(10):2829–38.
Kshema, George MJ, Dhas DAS. Preprocessing filters for mammogram images: A review. In: 2017 Conference on Emerging Devices and Smart Systems (ICEDSS) [Internet]. Mallasamudram, Tiruchengode, India: IEEE; 2017 [cited 2025 Aug 11]. p. 1–7. Available from: http://ieeexplore.ieee.org/document/8073694/
Zhang XH, Xiao C. Diagnostic Value of Nineteen Different Imaging Methods for Patients with Breast Cancer: a Network Meta-Analysis. Cell Physiol Biochem. 2018;46(5):2041–55.
Mammography [Internet]. National Institute of Biomedical Imaging and Bioengineering. [cited 2025 July 10]. Available from: https://www.nibib.nih.gov/science-education/science-topics/mammography
