Coronavirus Disease 2019 (Covid-19) has now become a concern around the world. Until 6 September 2020, there were 190,665 cases in Indonesia, and it was in the third rank of most cases in the Asian region. It is important to determine the criteria of return to work for healthcare workers with Covid-19 positive in Indonesia. This case report discussed a female patient, 32 years old with chief complaint of fever and itchy throat since 2 days ago. She is a health care worker in the hospital, with a history of treating patients with positive confirmation of Covid-19 for 2 days in the ordinary ward before the case was confirmed with a history of contact approximately 5 days ago. The patient was diagnosed with positive confirmation of Covid-19 and was required for self-isolation. The patient still had positive results of RT-PCR Covid-19 up to the third examination in 30 days after the initial RT-PCR testing, although received specific antiviral treatment with oral oseltamivir and oral supplementation. Based on growing evidence that Sars-Cov-2 may not infectious for more than ten days in the mild-moderate disease, this case report is strengthening the use of symptom-based strategic approach to determine when to return to work in Indonesian healthcare workers with positive COVID-19.
2. Singhal, T. A Review of Coronavirus Disease-2019 (COVID-19). Indian J. Pediatr. 87, 281–286 (2020).
3. Acter, T. et al. Evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as coronavirus disease 2019 (COVID-19) pandemic: A global health emergency. Sci. Total Environ. 730, 138996 (2020).
4. World Health Organization. Coronavirus disease (COVID-19) Weeklly Epidemiological Update. https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200907-weekly-epi-update-4.pdf?sfvrsn=f5f607ee_2 (2020).
5. Treibel, T. A. et al. COVID-19: PCR screening of asymptomatic health-care workers at London hospital. The Lancet 395, 1608–1610 (2020).
6. Sahu, A. K. et al. COVID-19 in health care workers – A systematic review and meta-analysis. Am. J. Emerg. Med. 38, 1727–1731 (2020).
7. Ministry of Health RI. Prevention and Controlling Guideline on Coronavirus Disease (COVID-19). (Ministry of Health RI, 2020).
8. Lin, A. et al. Early Risk Factors for the Duration of Severe Acute Respiratory Syndrome Coronavirus 2 Viral Positivity in Patients With Coronavirus Disease 2019. Clin. Infect. Dis. (2020) doi:10.1093/cid/ciaa490.
9. Fu, Y. et al. Risk factors for viral RNA shedding in COVID-19 patients. Eur. Respir. J. 56, 2001190 (2020).
10. Tomassini, S. et al. Setting the criteria for SARS-CoV-2 reinfection - six possible cases. J. Infect. (2020) doi:10.1016/j.jinf.2020.08.011.
11. Shrank, W. H. et al. A Simple Algorithm for Return to Workplace Employer Antibody Testing. Popul. Health Manag. 23, 346–349 (2020).
12. Sahu, K. K. & Cerny, J. A review on how to do hematology consults during COVID-19 pandemic. Blood Rev. 100777 (2020) doi:10.1016/j.blre.2020.100777.
13. Ghosh, S. et al. Imaging algorithm for COVID-19: A practical approach. Clin. Imaging 72, 22–30 (2020).
14. CDC. Criteria for Return to Work for Healthcare Personnel with SARS-CoV-2 Infection (Interim Guidance). Centers for Disease Control and Prevention https://www.cdc.gov/coronavirus/2019-ncov/hcp/return-to-work.html (2020).
15. Li, Z. et al. Development and clinical application of a rapid IgM‐IgG combined antibody test for SARS‐CoV‐2 infection diagnosis. J. Med. Virol. 92, 1518–1524 (2020).
16. Lou, B. et al. Serology characteristics of SARS-CoV-2 infection after exposure and post-symptom onset. Eur. Respir. J. 56, 2000763 (2020).
17. World Health Organization. Laboratory testing for coronavirus disease 2019 (COVID-19) in suspected human cases: interim guidance, 19 March 2020. World Health Organization. https://apps.who.int/iris/handle/10665/331500 (2020).
18. Lu, J. et al. Clinical, immunological and virological characterization of COVID-19 patients that test re-positive for SARS-CoV-2 by RT-PCR. EBioMedicine 59, 102960 (2020).
19. Sun, J. et al. Prolonged Persistence of SARS-CoV-2 RNA in Body Fluids. Emerg. Infect. Dis. 26, 1834–1838 (2020).
20. Gombar, S. et al. Persistent detection of SARS-CoV-2 RNA in patients and healthcare workers with COVID-19. J. Clin. Virol. 129, 104477 (2020).
21. Lan, L. et al. Positive RT-PCR Test Results in Patients Recovered From COVID-19. JAMA 323, 1502 (2020).
22. Chiba, S. Effect of early oseltamivir on outpatients without hypoxia with suspected COVID-19. Wien. Klin. Wochenschr. (2020) doi:10.1007/s00508-020-01780-0.
23. Wang, D. et al. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA 323, 1061–1069 (2020).